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                        What is CytoSpec?
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 The Multivariate Imaging Software package CytoSpec represents a novel approach for 
 creating pseudo-color displays of spectral imaging  data via statistical methods that utilize 
 the entire spectral information. It is laid out and optimized to work on 3-dimensional 
 spectral data sets from imaging or mapping infrared or Raman experiments. 
 Native data formats from from various instrument manufacturers can be analyzed. 

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                        Whats new in CytoSpec?
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    *    A VCA (vertex component analysis) imaging routine 

    *    Fuzzy C-means (FCM) clustering routine with enhanced functionality: A new option "
         composite image" was added. With CytoSpec 1.4.02 FCM can be carried out on the basis 
         of several interspectral distance measures: Euclidean, standardized Euclidean and 
         D-Values 

    *    Modifications of the k-means cluster (KMC) imaging routine: KMC imaging allows to 
         choose between several distance options: Euclidean, standardized Euclidean and 
         D-Values. An option for modifying the learning rate was also added.

    *    New import filter for NT-MDT Raman data (ASCII only)

    *    Added a new import filter for Kaiser-Raman Holospec data (ASCII only)

    *    WITec import filter updated 

    *    Added a new import filter for AFM and AFMIR data (Alex Dazzi/Universite Paris Sud) 

    *    Agglomerative hierarchical cluster imaging (HCA): dramatic speed improvements in 
         distance matrix calculation. Many thanks to Milos Miljkovic (from Max Diem lab at 
         Northeastern University) which provided the original source code. Speed advantage 
         by a factor of 20 and more! (Speed mode only)

    *    PCA imaging function  re-designed. Permits now also "basic" PCA imaging

    *    Function "rotate" with a new option for rotating by an arbitrary angle

    *    Pull-down menus re-arranged. With version 1.4.02 CytoSpec has now the a pulldown 
         menu "Univariate Imaging" (frequency, chemical imaging) and "Multivariate Imaging" 
         containing ANN/Cluster and VCA imaging functions

    *    3D-FSD is now a part of the preprocessing pulldown menu

    *    A new baseline correction routine added: polynomial baseline correction

    *    Inverted colormaps added: i-jet, i-hsv and i-hot for displaying maps from 
         derivative data 

    *    Perkin-Elmer and Bruker-OPUS import routines will load also incomplete maps (will 
         display an error message)

    *    Pre-processing function "subtract": subtraction of hyperspectral data sets by 
         internal or external vibrational spectra possible

    *    Macro programming for automated pre-processing added

    *    Many code improvements & bug fixes.

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                       GETTING STARTED - INSTALLATION
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       Once you have received the CytoSpec CD (or downloaded the zip-archive of the CytoSpec 
       demo version from CytoSpec's website), you are ready to install the program. During 
       the installation procedure CytoSpec's files will be automatically extracted from the 
       cabinet and all necessary steps for starting CytoSpec will be taken. 
       
       IMPORTANT: In order to run CytoSpec an additional license key file ('keygen.gen') 
                  must be copied into CytoSpec's main directory. This individual license 
                  key is NOT included in the CytoSpec CD and can be obtained only by 
                  sending a request by e-mail (order@CytoSpec.com). 

       * Open the Windows File Manager or Explorer. 

       * Locate the CytoSpec setup file on the CD you received. The file is named Setup.exe

       * To start the installation process just double click on setup.exe. The installation 
         program will be started automatically.

       * Determine the place on your harddisk where you want Cytospec to be installed. 
         Normally the proposed c:\program files\CytoSpec\CytoSpec will do fine. 

       * Then simply follow the instructions of the installation program.

       * When setup is complete you can find a new program group and a CytoSpec shortcut 
         on the desktop.

       * You can copy now the license key file into CytoSpec's main directory 
         (e.g. c:\program files\CytoSpec\CytoSpec)

       * Start the programm by double clicking on the CytoSpec icon.